Basics of Ototoxicity

OtotoxicitySimply put, Ototoxicity is ear poisoning; a poisoning of the nerves of the ear by drugs or chemicals.

There are certain drugs used to treat various medical conditions, and unfortunately, while attempting to cure or treat one issue, ototoxicity can occur and have damaging effects.

Several families of drugs can result in temporary or permanent hearing loss or balance problems. Below is a list of factors, causes and treatment information about Ototoxicity.

Ototoxicity factors include:

  • Age
  • Dosage of medication/Lifetime dose
  • Duration of therapy
  • Concurrent renal failure
  • Infusion rate (medication given intravenously better known as an IV)
  • Concurrent administration of another ototoxic drug
  • Family history of ototoxicity/Genetic susceptibility

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